➦ MAP kinase dynamics in response to pheromones in budding yeast
➦ Import of adenovirus DNA involves the nuclear pore complex receptor CAN/Nup214 and histone H1
➦ Desmoplakin is essential in epidermal sheet formation
➦ The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling
➦ Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly
➦ The GM130 and GRASP65 Golgi proteins cycle through and define a subdomain of the intermediate compar
➦ Differential contribution of cytoplasmic Ca2+ and Ca2+ influx to gamete fusion and egg activation in
➦ Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila
➦ Design and application of a cytokine-receptor-based interaction trap
➦ Recruitment of cohesin to heterochromatic regions by Swi6/HP1 in fission yeast
➦ The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos
➦ Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis
➦ Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair
➦ TGF-β induces apoptosis through Smad-mediated expression of DAP-kinase
➦ Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast
➦ Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2
➦ Yeast formins regulate cell polarity by controlling the assembly of actin cables
➦ The gated gait of the processive molecular motor, myosin V
➦ The exocyst is a Ral effector complex
➦ Association of human TFIID–promoter complexes with silenced mitotic chromatin in vivo
➦ The exocyst complex binds the small GTPase RalA to mediate filopodia formation
➦ Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus
➦ A small-molecule inhibitor of skeletal muscle myosin II
➦ A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies
➦ Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin
➦ Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes
➦ Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel part
➦ Identification of Sef, a novel modulator of FGF signalling
➦ IFN-Stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff
➦ Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition
➦ AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells
➦ IAPs are essential for GDNF-mediated neuroprotective effects in injured motor neurons in vivo
➦ Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling
➦ Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48
➦ α-Synuclein is phosphorylated in synucleinopathy lesions
➦ Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2–7 during G1 phase
➦ A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence
➦ Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex
➦ SMIF, a Smad4-interacting protein that functions as a co-activator in TGFβ signalling
➦ Arfaptin 2 regulates the aggregation of mutant huntingtin protein
➦ Polycystin-2 is an intracellular calcium release channel
➦ Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in y
➦ Myosin-X is an unconventional myosin that undergoes intrafilopodial motility
➦ A Drosophila APC tumour suppressor homologue functions in cellular adhesion
➦ Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI
➦ dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1
➦ Polyglycylation domain of β-tubulin maintains axonemal architecture and affects cytokinesis in Tetra
➦ Calcium-dependent membrane association sensitizes soluble guanylyl cyclase to nitric oxide