➦   NUP98–NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis

➦   Plasma membrane nanoswitches generate high-fidelity Ras signal transduction

➦   Regulated ATP release from astrocytes through lysosome exocytosis

➦   Multi-step pericellular proteolysis controls the transition from individual to collective cancer cel

➦   Cables links Robo-bound Abl kinase to N-cadherin-bound β-catenin to mediate Slit-induced modulation

➦   Genetic control of single lumen formation in the zebrafish gut

➦   Cathepsin L activity controls adipogenesis and glucose tolerance

➦   The Smc5–Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosom

➦   Exocytotic catecholamine release is not associated with cation flux through channels in the vesicle

➦   A reciprocal tensin-3–cten switch mediates EGF-driven mammary cell migration

➦   PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptio

➦   Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70

➦   Functional atlas of the integrin adhesome

➦   A concentration-dependent switch in the bacterial response to temperature

➦   Toll-like receptors modulate adult hippocampal neurogenesis

➦   Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic

➦   S-nitrosylation of microtubule-associated protein 1B mediates nitric-oxide-induced axon retraction

➦   The F-box protein Fbl10 is a novel transcriptional repressor of c-Jun

➦   The lipid droplet is an important organelle for hepatitis C virus production

➦   Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria du

➦   Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 comple

➦   A proteomic screen reveals SCFGrr1 targets that regulate the glycolytic–gluconeogenic switch

➦   Polycomb response elements mediate the formation of chromosome higher-order structures in the bithor

➦   Motor-free mitochondrial presequence translocase drives membrane integration of preproteins

➦   Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum