➦   The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia

➦   Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled bin

➦   MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

➦   Endosome-to-cytosol transport of viral nucleocapsids

➦   S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

➦   The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP

➦   Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models

➦   DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

➦   NudEL targets dynein to microtubule ends through LIS1

➦   Telomere fusion to chromosome breaks reduces oncogenic translocations and tumour formation

➦   Protein kinase activity of phosphoinositide 3-kinase regulates β-adrenergic receptor endocytosis

➦   Cdc2–cyclin E complexes regulate the G1/S phase transition

➦   Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes

➦   A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signall

➦   Temporal and spatial control of nucleophosmin by the Ran–Crm1 complex in centrosome duplication

➦   Prohibitin is required for Ras-induced Raf–MEK–ERK activation and epithelial cell migration

➦   A GTPase-activating protein controls Rab5 function in endocytic trafficking

➦   Load-dependent kinetics of myosin-V can explain its high processivity

➦   Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinosito

➦   PDGFRβ+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular surv

➦   Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization

➦   Listeria hijacks the clathrin-dependent endocytic machinery to invade mammalian cells

➦   Clusterin inhibits apoptosis by interacting with activated Bax

➦   Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation

➦   Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochr