➦   HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppresse

➦   HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reser

➦   Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation

➦   Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug a

➦   The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulenc

➦   Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells

➦   T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experiment

➦   A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box–bindin

➦   Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted t

➦   The regulatory subunits of PI3K, p85α and p85β, interact with XBP-1 and increase its nuclear translo

➦   Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorr

➦   Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding c

➦   Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions

➦   Multispectral scanning during endoscopy guides biopsy of dysplasia in Barrett's esophagus

➦   A CD8+ T cell transcription signature predicts prognosis in autoimmune disease

➦   Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy

➦   Disruption of antigenic variation is crucial for effective parasite vaccine

➦   PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2

➦   Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive–like behavior

➦   Methylation determines fibroblast activation and fibrogenesis in the kidney

➦   Memory CD4+ T cells induce innate responses independently of pathogen

➦   Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

➦   The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+

➦   Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymph

➦   Epidermal growth factor receptor is a co-receptor for adeno-associated virus serotype 6

➦   ERK activation drives intestinal tumorigenesis in Apcmin/+ mice

➦   In vivo prevention of transplant arteriosclerosis by ex vivo–expanded human regulatory T cells

➦   Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke–induced pulmonar

➦   Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoar

➦   Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection

➦   A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in mal

➦   Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

➦   Basophils and the T helper 2 environment can promote the development of lupus nephritis

➦   In vivo tracking of 'color-coded' effector, natural and induced regulatory T cells in the allograft

➦   An autoimmune-mediated strategy for prophylactic breast cancer vaccination

➦   Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activ

➦   Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

➦   Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse e

➦   Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disea

➦   Organ reengineering through development of a transplantable recellularized liver graft using decellu

➦   Serotonin regulates pancreatic beta cell mass during pregnancy

➦   Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a

➦   Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

➦   Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy

➦   Regeneration and orthotopic transplantation of a bioartificial lung

➦   Lipid accumulation and dendritic cell dysfunction in cancer

➦   CIB1 is a regulator of pathological cardiac hypertrophy

➦   A molecularly engineered split reporter for imaging protein-protein interactions with positron emiss

➦   Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation

➦   Dissolving polymer microneedle patches for influenza vaccination