➦   Scavenger receptor B2 is a cellular receptor for enterovirus 71

➦   Human P-selectin glycoprotein ligand-1 is a functional receptor for enterovirus 71

➦   Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease

➦   Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining infl

➦   A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth

➦   Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nerv

➦   Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates

➦   TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

➦   Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bo

➦   Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes

➦   Baseline Ad5 serostatus does not predict Ad5 HIV vaccine–induced expansion of adenovirus-specific CD

➦   Sex differences in the Toll-like receptor–mediated response of plasmacytoid dendritic cells to HIV-1

➦   Normalization of obesity-associated insulin resistance through immunotherapy

➦   Adenovirus-specific immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans

➦   CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesit

➦   Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metab

➦   Roadblocks in HIV research: five questions

➦   Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and d

➦   Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1

➦   Persistence of HIV-1 receptor–positive cells after HSV-2 reactivation is a potential mechanism for i

➦   A new human immunodeficiency virus derived from gorillas

➦   Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain i

➦   Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhib

➦   A granulocyte-macrophage colony–stimulating factor and interleukin-15 fusokine induces a regulatory

➦   A rapid and efficient single-cell manipulation method for screening antigen-specific antibody–secret

➦   Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis

➦   Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis

➦   Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis

➦   A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell res

➦   Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy

➦   Dual and opposing roles of primary cilia in medulloblastoma development

➦   NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

➦   Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successf

➦   Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis

➦   A crucial role for adipose tissue p53 in the regulation of insulin resistance

➦   Impaired Wnt–β-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopa

➦   Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse

➦   An integrin αvβ3–c-Src oncogenic unit promotes anchorage-independence and tumor progression

➦   Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy

➦   Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain im

➦   The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neuro

➦   Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity ag

➦   Dual roles for hepatic lectin receptors in the clearance of chilled platelets

➦   Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis

➦   Development of universal antidotes to control aptamer activity

➦   Inhibition of the c-Abl–TAp63 pathway protects mouse oocytes from chemotherapy-induced death

➦   Major histocompatibility complex genotyping with massively parallel pyrosequencing

➦   Matrix-insensitive protein assays push the limits of biosensors in medicine

➦   Foxo1 integrates insulin signaling with mitochondrial function in the liver

➦   PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance