➦   Chemical control of protein stability and function in living mice

➦   Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology

➦   Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis

➦   The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis

➦   Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangiom

➦   HIT: a versatile proteomics platform for multianalyte phenotyping of cytokines, intracellular protei

➦   Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis

➦   The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

➦   Engineering microRNA responsiveness to decrease virus pathogenicity

➦   Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal

➦   5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

➦   Highly cited papers on reproductive biology (2005–2007)

➦   Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor

➦   Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor a

➦   Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macr

➦   Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex

➦   Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and tox

➦   Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

➦   A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative abilit

➦   A role for leukocyte-endothelial adhesion mechanisms in epilepsy

➦   Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidne

➦   Targeting inside-out phosphatidylserine as a therapeutic strategy for viral diseases

➦   Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung can

➦   BMP type I receptor inhibition reduces heterotopic ossification

➦   Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes

➦   A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy

➦   Neurotoxic autoantibodies mediate congenital cortical impairment of offspring in maternal lupus

➦   Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced re

➦   Dcx reexpression reduces subcortical band heterotopia and seizure threshold in an animal model of ne

➦   γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

➦   Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipi

➦   MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis

➦   A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer

➦   Development of a novel mouse glioma model using lentiviral vectors

➦   AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin defici

➦   Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon

➦   The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases

➦   Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalop

➦   Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent man

➦   Regulation of cardiovascular development and integrity by the heart of glass–cerebral cavernous malf

➦   De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury

➦   In situ genetic analysis of cellular chimerism

➦   NAMPT is essential for the G-CSF–induced myeloid differentiation via a NAD+–sirtuin-1–dependent path

➦   Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

➦   Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

➦   A replication clock for Mycobacterium tuberculosis

➦   Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells

➦   Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheim

➦   Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simia

➦   Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase