➦   Adiponectin-mediated modulation of hypertrophic signals in the heart

➦   Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

➦   Therapeutic dendritic-cell vaccine for chronic HIV-1 infection

➦   Protein microarrays for multiplex analysis of signal transduction pathways

➦   The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption

➦   Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel

➦   Inhibition of respiratory viruses by nasally administered siRNA

➦   Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting th

➦   Tissue-print and print-phoresis as platform technologies for the molecular analysis of human surgica

➦   Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian

➦   Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3-galactosy

➦   Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

➦   Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death

➦   Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

➦   Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry

➦   Heart transplantation in baboons using α1,3-galactosyltransferase gene-knockout pigs as donors: init

➦   Accelerated re-epithelialization in β3-integrin-deficient- mice is associated with enhanced TGF-β1 s

➦   Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease

➦   Re-engineered CD40 receptor enables potent pharmacological activation of dendritic-cell cancer vacci

➦   Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity

➦   Experimental autoimmune encephalomyelitis repressed by microglial paralysis

➦   Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization

➦   Cathepsin L is required for endothelial progenitor cell–induced neovascularization

➦   Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

➦   Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB

➦   Uridine adenosine tetraphosphate: a novel endothelium- derived vasoconstrictive factor

➦   IKK-β links inflammation to obesity-induced insulin resistance

➦   Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabeti

➦   Human embryonic stem cells express an immunogenic nonhuman sialic acid

➦   Spontaneous fetal loss caused by placental thrombosis in estrogen sulfotransferase—deficient mice

➦   Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene

➦   The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins int

➦   Lentiviral vector retargeting to P-glycoprotein on metastatic melanoma through intravenous injection

➦   Vav3 regulates osteoclast function and bone mass

➦   Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals

➦   Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy

➦   G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in

➦   Regulation of NKT cell development by SAP, the protein defective in XLP

➦   Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells

➦   EIF2B5 mutations compromise GFAP+ astrocyte generation in vanishing white matter leukodystrophy

➦   Contribution of bone marrow–derived endothelial cells to human tumor vasculature

➦   The fibrin-derived peptide Bβ15–42 protects the myocardium against ischemia-reperfusion injury

➦   Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis

➦   Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis

➦   Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndro

➦   Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis

➦   Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression

➦   The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis

➦   Angiopoietin-related growth factor antagonizes obesity and insulin resistance

➦   Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS m