➦   P2X7 receptor inhibition improves recovery after spinal cord injury

➦   A role for Streptococcus pneumoniae in virus-associated pneumonia

➦   Systemic delivery of genes to striated muscles using adeno-associated viral vectors

➦   Effector CD8+ T cells mediate inflammation and airway hyper-responsiveness

➦   Mouse model of Noonan syndrome reveals cell type– and gene dosage–dependent effects of Ptpn11 mutati

➦   Trans-splicing repair of CD40 ligand deficiency results in naturally regulated correction of a mouse

➦   Reticulon family members modulate BACE1 activity and amyloid-β peptide generation

➦   Donor APCs are required for maximal GVHD but not for GVL

➦   Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity

➦   Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin

➦   The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm

➦   Degenerate self-reactive human T-cell receptor causes spontaneous autoimmune disease in mice

➦   Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphede

➦   Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predict

➦   Tumor-infiltrating dendritic cell precursors recruited by a β-defensin contribute to vasculogenesis

➦   The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human c

➦   Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission

➦   CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation

➦   Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator

➦   Volumetric computed tomography (VCT): a new technology for noninvasive, high-resolution monitoring o

➦   Aberrant cannabinoid signaling impairs oviductal transport of embryos

➦   Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization

➦   Modeling epidemics of multidrug-resistant M. tuberculosis of heterogeneous fitness

➦   Modeling the emergence of the 'hot zones': tuberculosis and the amplification dynamics of drug resis

➦   Selective inactivation or reconstitution of adenosine A2A receptors in bone marrow cells reveals the

➦   4-1BB-mediated immunotherapy of rheumatoid arthritis

➦   Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide

➦   Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway

➦   Nonsteroidal anti-inflammatory drugs lower Aβ42 and change presenilin 1 conformation

➦   Central memory T cells mediate long-term immunity to Leishmania major in the absence of persistent p

➦   Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smo

➦   TCR affinity and negative regulation limit autoimmunity

➦   S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide

➦   Cardiomyocyte-restricted peroxisome proliferator-activated receptor-δ deletion perturbs myocardial f

➦   Heparin prevents antiphospholipid antibody–induced fetal loss by inhibiting complement activation

➦   Enhanced insulin sensitivity, energy expenditure and thermogenesis in adipose-specific Pten suppress

➦   Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis

➦   Donor-specific B-cell tolerance after ABO-incompatible infant heart transplantation

➦   Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally ac

➦   The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers

➦   Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resist

➦   Dissecting tumor maintenance requirements using bioluminescence imaging of cell proliferation in a m

➦   Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C

➦   Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation

➦   Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lympho

➦   Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from stat

➦   Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy

➦   Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection

➦   Prevention of cholesterol gallstone disease by FXR agonists in a mouse model

➦   Small molecule RITA binds to p53, blocks p53–HDM-2 interaction and activates p53 function in tumors