➦   Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants

➦   CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

➦   Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging

➦   Calreticulin exposure dictates the immunogenicity of cancer cell death

➦   Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling

➦   A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protei

➦   Tropism of avian influenza A (H5N1) in the upper and lower respiratory tract

➦   Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection

➦   Dickkopf-1 is a master regulator of joint remodeling

➦   Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein

➦   Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability thr

➦   Angiotensin II type 1 receptor blockade attenuates TGF-β–induced failure of muscle regeneration in m

➦   Promotion of sleep by targeting the orexin system in rats, dogs and humans

➦   Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide

➦   Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity

➦   Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic ac

➦   Disruption of methylarginine metabolism impairs vascular homeostasis

➦   Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins

➦   Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure

➦   Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1

➦   β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione tre

➦   Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3β activity

➦   In vivo imaging of siRNA delivery and silencing in tumors

➦   Humanization of autoantigen

➦   Highly cited papers on tuberculosis (2003–2005)

➦   The top twenty papers on tuberculosis

➦   IFN-γ mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial i

➦   Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

➦   Langerin is a natural barrier to HIV-1 transmission by Langerhans cells

➦   ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor

➦   MRI detection of transcriptional regulation of gene expression in transgenic mice

➦   Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like diseas

➦   Bone marrow–specific Cap gene deletion protects against high-fat diet–induced insulin resistance

➦   Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease

➦   CD8+ T-cell responses to adeno-associated virus capsid in humans

➦   Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes

➦   Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation

➦   Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood

➦   Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase

➦   Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB

➦   The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and

➦   Angiogenic inhibition reduces germinal matrix hemorrhage

➦   Derivation of engraftable skeletal myoblasts from human embryonic stem cells

➦   Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy

➦   Noninvasive detection of macrophages using a nanoparticulate contrast agent for computed tomography

➦   Sema3a maintains normal heart rhythm through sympathetic innervation patterning

➦   MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitme

➦   Cyclic AMP–regulated exocytosis of Escherichia coli from infected bladder epithelial cells

➦   Rhesus monkey TRIM5α restricts HIV-1 production through rapid degradation of viral Gag polyproteins

➦   Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subse