➦   Antielastin autoimmunity in tobacco smoking–induced emphysema

➦   The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

➦   MicroRNA-133 controls cardiac hypertrophy

➦   SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes

➦   Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals

➦   An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS

➦   Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria

➦   Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and

➦   TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1

➦   The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas

➦   Neutralization of staphylococcal enterotoxin B by soluble, high-affinity receptor antagonists

➦   Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia

➦   Restoration of cone vision in a mouse model of achromatopsia

➦   Abrogation of nuclear receptors Nr4a3 andNr4a1 leads to development of acute myeloid leukemia

➦   Mast cells promote atherosclerosis by releasing proinflammatory cytokines

➦   Retinaldehyde represses adipogenesis and diet-induced obesity

➦   Identification of a key pathway required for the sterile inflammatory response triggered by dying ce

➦   Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

➦   Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC

➦   Engineering functional two- and three-dimensional liver systems in vivo using hepatic tissue sheets

➦   A GABAergic system in airway epithelium is essential for mucus overproduction in asthma

➦   Fen1 mutations result in autoimmunity, chronic inflammation and cancers

➦   Real-time measurement of free Ca2+ changes in CNS myelin by two-photon microscopy

➦   Increased dietary intake of ω-3-polyunsaturated fatty acids reduces pathological retinal angiogenesi

➦   Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced obesity and

➦   Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer

➦   Genital transmission of HPV in a mouse model is potentiated by nonoxynol-9 and inhibited by carragee

➦   α1β1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis

➦   Essential role of stromally induced hedgehog signaling in B-cell malignancies

➦   E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury

➦   Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells

➦   Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair

➦   IL-15 constrains mast cell–dependent antibacterial defenses by suppressing chymase activities

➦   DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection

➦   Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes af

➦   Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

➦   Type II monocytes modulate T cell–mediated central nervous system autoimmune disease

➦   Magnetic resonance–guided, real-time targeted delivery and imaging of magnetocapsules immunoprotecti

➦   A spatially and temporally restricted mouse model of soft tissue sarcoma

➦   Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea

➦   Molecular imaging of Akt kinase activity

➦   The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers

➦   CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes

➦   Clearance of amyloid-β by circulating lipoprotein receptors

➦   Lack of Fas antagonism by Met in human fatty liver disease

➦   Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radi

➦   High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

➦   Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype

➦   Broad HIV-1 neutralization mediated by CD4-binding site antibodies

➦   A ligand-receptor fusion of growth hormone forms a dimer and is a potent long-acting agonist